Influence of Automatic Oxygen Titration Device (FreeO2) on Percentage of Time Within Oxygen Saturation Target and Induced Hypercapnia During Noninvasive Ventilation for Patients Hospitalized for an Acute Exacerbation of COPD or a Bariatric Surgery

Status: Recruiting
Location: See location...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients. The main hypothesis is that FreeO2 device for oxygen therapy associated with NIV or nasal high flow oxygen therapy (NHFOT) allows to reach better oxygenation and avoid hypoxemia and hyperoxia.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Respiratory acidosis (pH \<= 7.35 and PaCO2 \> 45 mmHg), with or without NIV (last blood gas available during hospitalization)

• Oxygen therapy and/or SpO2 \<90% room air (FiO2 \<= 50% or nasal cannula \<= 7 L/min to maintain SpO2 90%)

• High flow nasal cannula with flow \<= 30 L/min

• Patients using CPAP before the surgery (obstructive sleep apnea documented).

• Patients with obesity hypoventilation syndrome in addition to obstructive sleep apnea can be included.

Locations
Other Locations
Canada
Institut universitaire de Cardiologie et de Pneumologie - Université Laval
RECRUITING
Québec
Contact Information
Primary
François Lellouche, MD, PhD
Francois.Lellouche@criucpq.ulaval.ca
418-656-8711
Backup
Miguel Trottier, MD, CM
miguel.trottier.1@ulaval.ca
Time Frame
Start Date: 2019-10-28
Estimated Completion Date: 2028-06
Participants
Target number of participants: 10
Treatments
Other: COPD patients
Patients with acute exacerbation of COPD and respiratory acidosis under oxygen therapy.
Other: Bariatric surgery patients
Obese patients after gastric surgery under CPAP.
Sponsors
Leads: François Lellouche

This content was sourced from clinicaltrials.gov